|
Traditional Methods |
Molecular Methods |
Sample Turnaround Time |
1-2 weeks (culturable samples) |
1-2 days on any sample |
Data Quality |
Can be variable based upon analyst and experience |
Instrument-based data |
Aspergillus / Penicillium Differentiation |
Requires 1-2 weeks |
Requires 1-2 days |
Detection System |
Microscopical detection utilizing color, size and morphology of mold |
Highly sensitive instrument-based detection relying on DNA sequence |
Sampling Times |
Typically short term sampling |
Able to take long term samples |
Background Interference Potential |
Dust particulate can cause interference on Air-O-Cells, Burkhards, Allergenco, tape lifts, or bulk non-viable direct exams |
Particulate in the sample not an interference as PCR will not amplify non-targeted material; Clean up of samples available |